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What is the Efficacy of Tetra Hydro Curcuminoids? | Anzen Exports

February 26, 2021by Anzen_Exports0

Tetra hydro curcuminoids is a metabolite of curcumin that is effective on cancer, osteoarthritis, canker sore, gingivitis. Compared to Curcumin, tetra hydro curcuminoids (THCs) have higher therapeutic effects, physiological stability, and bioavailability. Its antioxidative activity, chemical stability, and solubility in water are more than curcumin, which augments the mechanism of action.

Tetra hydro curcuminoids benefits have a range of pharmaceutical properties. It is nephroprotective, cardioprotective, antidiabetic, anti-malignant, antimicrobial, hepatoprotective, anti-inflammatory, and more.

To better understand THCs, one must know what is curcumin? It is a yellow crystalline bioactive compound present in turmeric. It has broad-spectrum medicinal benefits. THC is a hydrogenated product extracted from curcumin. Out of 30 other metabolites of curcumin, it is one of the most valued metabolite. Metabolite means a substance necessary for metabolism or the conversion process of curcumin into energy for supporting the body to function. (1)

Canker Sore Treatment

By treating with THCs, Vital Analog Scale pain score, canker sore, throat numbness, and multi lesions patients get well.21 days of treatment with 100mg THCs tablets can get a complete cure.  It recovers inflammation, redness, pain, and canker sore. (2)

The efficacy of THCs in treating the above-mentioned health conditions are registered in Clinical Trial Registry in India. This clinical trial was held at Noble Hospital of Pune. (3)

Also readCurcumin, The Miracle Immunity Ingredient



This is a disease that refers to the inflammation of the gums. In this case, the gums swell and bleed along with severe pain. The supplementation of THCs prevents the progression of diseases, cures the entire syndrome and associated pain. Its polyphenol benefits are persuasive in this aspect.

The pharmacological and physiological properties of curcumin and THCs are the same; however, the molecular structure differs. This makes it a step ahead of curcumin or turmeric, an antioxidant food.


In the vitro and vivo model of research, THCs have anti-cancer efficacy. It is pro-oxidant properties modulate oxidative stress, metastasis, xenobiotic detoxification, programmed cell death, and boost immunity.

Curcumin has an anti-cancer effect; however, its low bioavailability limits the pharmacological benefits. In this aspect, THC has better solubility, bioavailability, and chemical stability.

Its chemical characteristics, distinguishable molecular targets, biological properties augment medicinal effect on cancer. It is highly effective on signs of colorectal cancer. THC has a better scavenging effect, therefore, is more effective.

Rheumatoid Arthritis

THC is an effective treatment for rheumatoid arthritis. It is anti-inflammatory and relieves any chronic or acute inflammation problem. It has anti-oxidative and inhibitory effects as a result of β-diketone moiety and a combination of the phenolic hydroxy group. The antioxidant enzymes present in THC are chemo-preventive. Those enzymes are:

  • Glutathione peroxidase
  • S-trans
  • Glutathione
  • S-transferase
  • NADPH quinone reductase (4)

Other Benefits of Tetra Hydro Curcuminoids

THC has several other health advantages. It recovers the problem related to trouble breathing, skin problems, aging, digestive disorder as well as helps boost immunity.

THC is available as nutraceutical extracts, which makes nutraceutical finished products. With growing awareness about curcumin, researchers and consumers are keen on using its refined components.

Products of Anzen Exports

Anzen Exports is one of the leading exporters of Active Pharmaceutical Ingredients, nutraceutical extracts, and herbal extracts. Tetra Hydro Curcuminoids are exported by us to companies across the world producing nutraceutical products.

A sister company of Anzen Exports is producing and marketing nutraceutical products. To know more about our products and topics related to health and benefits read our upcoming blogs.


Anzen Exports’ blog posts are based just on our research from cited websites. To be best informed, we advise consulting a doctor about an ingredient or medicine prior to taking it.



  1. NCBI

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  1. Hindawi

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  1. Clinical Trials Registry – India

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  1. Science Direct

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