Deflazacort is a medicine used to treat Duchenne muscular dystrophy (DMD) in adults and children over the age of two. DMD is a genetic condition caused by abnormalities in the dystrophin gene, essential for muscle function. It can induce significant muscular weakness and progressive respiratory and cardiovascular impairment.
While Deflazacort does not cure muscular dystrophy, it may strengthen the muscles and delay the onset of disability. It works by preventing the release of substances in the body that cause inflammation.
Deflazacort belongs to a class of medications known as corticosteroids. In addition to slowing down the effects of DMD, it has fewer side effects on bone health and weight than other corticosteroids.
The dosage for Deflazacort is determined by the doctor based on the patient’s body weight. The medication is available as oral suspension and tablets.
The dosage is approximately 0.9 mg/kg daily for adults and children two years or older. It must be taken as directed and for the duration prescribed by the doctor.
Deflazacort is not recommended for patients allergic to the active ingredient or other components in the medication. In case of allergic symptoms, you should contact the doctor immediately. Children under the age of two should not be administered Deflazacort. Deflazacort oral suspension (liquid) contains chemicals lethal to newborns or premature babies.
The body experiences significant side effects from long-term use. It can cause osteoporosis, especially if you smoke, have a family history of the disease, etc.
Using Deflazacort at any point during pregnancy may affect the newborn baby’s adrenal gland hormones. Inform your doctor if your baby exhibits signs such as dry skin, weakness, feeding difficulties, or vomiting. Breastfeeding may be unsafe when taking Deflazacort. Inquire with your doctor about the risks of taking Deflazacort while expecting or planning to become pregnant.
Some common side-effects of Deflazacort are the following-
- thin, fragile skin
- red or purple blotches or lines under the skin
- increased hair growth
- bulging eyes
- irregular or absent periods
- slowed healing of cuts and bruises
- changes in the way fat is spread around the body
- weak muscles
- joint pain
- frequent urination during the daytime
- difficulty falling asleep or staying asleep
- increased appetite
Some severe side-effects of Deflazacort are the following-
- sore throat, fever, chills, cough, or other signs of infection
- eye pain, redness, or tearing
- swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
- difficulty breathing or swallowing
- sudden weight gain
- peeling or blistering skin
- stomach pain
- extreme changes in mood or changes in personality
- inappropriate happiness
It is imperative to consult a doctor about the risks of using Deflazacort before use.
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Anzen Export’s blog posts have been written with information gathered from approved medical journals and websites online. Our research and technical team strive to provide relevant information through such articles. To be best informed, we advise consulting a doctor about an ingredient or medicine before taking it.