Table of Contents
How is Bromelain Extracted?
The enzyme bromelain is present in all parts of the pineapple, however, bromelain available from the stem is beneficial for therapeutic purposes. To make the pineapple enzyme or bromelain, the following processes are applicable:
- Centrifugation
- Ultrafiltration
- Lyophilisation
- Fast protein liquid chromatography (2)
Also Read – Benefits of Green Coffee Extract for Weight Loss & Skin Care
What is the Chemical Content of Bromelain?
Thiol endopeptidases, various protease inhibitors, and the following other chemicals comprise Bromelain:
- Phosphatase
- Glucosidase
- Peroxidase
- Cellulase
- Escharase (3)
Which Health Conditions is Bromelain effective on?
Vitro implies the experiments performed outside a living organism and vivo means the research done within the living organism. (4) According to the demonstration of vitro and vivo studies, bromelain is anti-inflammatory, anti-edematous, anti-thrombotic, and fibrinolytic. Fibrinolysis means the properties, which prevent blood from clotting. (5) Bromelain is effective on following health conditions:
- Digestive disorders
- Sinus problems
- Skin burns
- Angina pectoris
- Bronchitis
- Surgical trauma
- Thrombophlebitis
- Wounds debridement
- Osteoarthritis
- Cardiovascular disorders (6)
How is Bromelain Absorbed by the Blood?
Our body can absorb 12gm of Bromelain per day in a functionally undamaged form through the gastrointestinal tract. However, 40% of Bromelain is absorbed through the intestine in molecular form.
Bromelain gets linked with alpha 1-antichymotrypsin and alpha 2-macroglobulinm, which are antiproteinase of blood.
It is used in skin cream and is absorbed by the cutaneous membrane to help the skin recover from ailments. (7)
What are the side effects of Bromelain?
Stomach discomfort, diarrhoea, and allergy are some common side effects of Bromelain. Those who are prone to allergies must refrain from taking Bromelain as it triggers the allergic reaction.
It is advisable not to take Bromelain within 2 hours after surgery, as it enhances the risk of bleeding. (8)
Contraindications:
- Amoxicillin
- Tetracycline
- Anticoagulant
- Antiplatelet
Bromelain in Nutraceutical Industry
Bromelain is widely used in the nutraceutical industry as a dietary supplement and also in the making of topical creams. Bromelain extracts, in combination with other components, make the finished products.
Anzen Exports is one of the leading suppliers of nutraceutical extracts. We source Bromelain extract from authentic manufactures and supply it to the companies producing natural cosmetics or dietary supplements.
It is available in the market in the form of a pill, tablet, and cream. Having raw pineapple is not adequate enough to derive Bromelain in the required amount. Please take the advice of a doctor or a nutritionist before intaking Bromelain. Intaking nutraceutical products protects one from diseases and helps maintain good health. Read our upcoming blogs to get insight on various nutrients, modes of intake, and their benefits.
Disclaimer:
Anzen Exports’ blog posts are based just on our research from cited websites. To be best informed, we advise consulting a doctor about an ingredient or medicine prior to taking it.
Sources:
- Healthline
Website – https://www.healthline.com/health/bromelain - Scielo
Website – http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100315#:~:text=The%20marketable%20bromelain%20is%20mostly,Harrach%20et%20al.%201998). - Hindawi
Website – https://www.hindawi.com/journals/btri/2012/976203/ - Healthline
Website – https://www.healthline.com/health/in-vivo-vs-in-vitro#takeaway - Medline Plus
Website – https://medlineplus.gov/ency/article/000577.htm#:~:text=Fibrinolysis%20is%20a%20normal%20body,%2C%20medicine%2C%20or%20other%20cause. - NCBI
Website – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/ - Hindwai
Website – https://www.hindawi.com/journals/btri/2012/976203/ - WeMD
Website – https://www.webmd.com/vitamins/ai/ingredientmono-895/bromelainÂ